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Anti-SMEK1 Antibody

品牌：Antibodies

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规格：50µl

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Anti-SMEK1 Antibody

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Name:	Anti-SMEK1 Antibody See all SMEK1 primary antibodies
Description:	Rabbit polyclonal antibody to SMEK1.
Applications:	WB, IHC
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:100.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant Protein of human SMEK1.
Protein Length:	833 (594)
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Sequence Similarities:	Belongs to the SMEK family.
Cellular locations:	Cytoplasm. Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome. Nucleus. In interphase localized in the cytoplasm and in the nucleus (with higher levels). During metaphase located in pericentriolar regions.
Database Links:	Entrez Gene: 55671?Human Entrez Gene: 68734?Mouse Entrez Gene: 314388?Rat Omim: 610351?Human SwissProt: Q6IN85?Human SwissProt: Q6P2K6?Mouse Unigene: 533887?Human Unigene: 87077?Mouse
Synonyms:	FLFL1 Antibody KIAA2010 Antibody MEK1 SUPPRESSOR 1 Antibody MSTP033 Antibody P4R3A_HUMAN Antibody PP4R3 Antibody PP4R3 ALPHA Antibody PP4R3A Antibody PPP4R3A Antibody Protein phosphatase 4 regulatory subunit 3A Antibody PROTEIN PHOSPHATASE 4, REGULATORY SUBUNIT 3, ALPHA Antibody Serine/threonine-protein phosphatase 4 regulatory subunit 3A Antibody SMEK homolog 1 Antibody SMEK homolog 1, suppressor of mek1 (Dictyostelium) Antibody Smek1 Antibody Smk 1 Antibody SMK1 Antibody
Information:	Target information shown above is from the UniProt Consortium.