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Anti-SCYL1 Antibody

品牌：Antibodies

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规格：50µl

货期：

应用：

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Anti-SCYL1 Antibody

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Overview

Name:	Anti-SCYL1 Antibody See all SCYL1 primary antibodies
Description:	Rabbit polyclonal antibody to SCYL1.
Applications:	WB, IHC, IF
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100.
Reactivity:	Human, Rat
Immunogen:	Recombinant protein of human SCYL1.
Protein Length:	808
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum (PubMed:18556652). Involved in the maintenance of the Golgi apparatus morphology (PubMed:26581903). Has no detectable kinase activity in vitro (PubMed:18556652).
Tissue Specificity:	Ubiquitous.
Involvement in Disease:	Spinocerebellar ataxia, autosomal recessive, 21: A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCAR21 is characterized by cerebellar atrophy and ataxia with onset in early childhood. Patients also manifest recurrent episodes of liver failure, hepatic fibrosis and a peripheral neuropathy.
Sequence Similarities:	Belongs to the protein kinase superfamily.
Cellular locations:	Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome. Endoplasmic reticulum-Golgi intermediate compartment. Golgi apparatus > cis-Golgi network. Localized to the Endoplasmic reticulum-Golgi intermediate and cis-Golgi in an ARF1-independent manner.
Database Links:	Entrez Gene: 57410?Human Entrez Gene: 293684?Rat Omim: 607982?Human SwissProt: Q96KG9?Human SwissProt: Q5M9F8?Rat Unigene: 238839?Human Unigene: 143751?Rat
Synonyms:	Coated vesicle associated kinase of 90 kDa Antibody Coated vesicle-associated kinase of 90 kDa Antibody CVAK90 Antibody GKLP Antibody HT019 Antibody Likely ortholog of mouse N terminal kinase like protein Antibody MGC78454 Antibody N terminal kinase like Antibody N terminal kinase like protein Antibody N-terminal kinase-like protein Antibody NKTL Antibody NTKL Antibody NTKLBP1 Antibody NTKL_HUMAN Antibody P105 Antibody SCY L1 Antibody SCY1 like 1 Antibody SCY1 like 1 protein 1 Antibody SCY1-like protein 1 Antibody SCYL 1 Antibody SCYL1 Antibody SCYL1BP1 Antibody TAPK Antibody TEIF Antibody Telomerase regulation associated protein Antibody Telomerase regulation-associated protein Antibody Telomerase transcriptional element interacting factor Antibody Telomerase transcriptional element-interacting factor Antibody Teratoma associated tyrosine kinase Antibody Teratoma-associated tyrosine kinase Antibody TRAP Antibody
Information:	Target information shown above is from the UniProt Consortium.