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Anti-RPL13A Antibody |产品详情|进口橙子视频旧款采购网




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    Anti-RPL13A Antibody
    品牌:Antibodies
    货号:
    规格:100µl
    货期:

    Anti-RPL13A Antibody

    商品详情 参考文献 相关资料
    Name: Anti-RPL13A Antibody
    See all RPL13A primary antibodies
    Description: Rabbit polyclonal antibody to RPL13A
    Applications: WB, IHC, IF
    Reactivity: Human
    Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 197 of Human RPL13A
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: Purified by antigen-affinity chromatography.
    Formulation: Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
    Storage: Store at -20?C for long term preservation (recommended). Store at 4?C for short term use.
    Function: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3- and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA.
    Sequence Similarities: Belongs to the universal ribosomal protein uL13 family.
    Post-Translational Modification: Phosphorylation at Ser-77 upon interferon-gamma treatment in monocytes involves a DAPK1-DAPK3 kinase cascade and is causing release from the ribosome, association with the GAIT complex and subsequent involvement in transcript-selective translation inhibition.
    Cellular locations: Cytoplasm.
    Database Links:
  • Entrez Gene: 23521?Human
  • SwissProt: P40429?Human
  • Synonyms:
  • 23 kD highly basic protein Antibody
  • 23 kDa highly basic protein Antibody
  • 60S ribosomal protein L13a Antibody
  • L13A Antibody
  • P198 Antibody
  • Ribosomal protein L13a Antibody
  • RPL 13A Antibody
  • RPL13A Antibody
  • Tissue specific transplantation antigen 1 Antibody
  • Transplantation antigen P198 Antibody
  • TSTA1 Antibody
  • Tstap198 7 Antibody
  • Tum antigen Antibody
  • Tum P198 antigen Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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