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Anti-ANGPTL4 Antibody |产品详情|进口橙子视频旧款采购网




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    Anti-ANGPTL4 Antibody
    品牌:Antibodies
    货号:
    规格:100µl
    货期:

    Anti-ANGPTL4 Antibody

    商品详情 参考文献 相关资料
    Name: Anti-ANGPTL4 Antibody
    See all ANGPTL4 primary antibodies
    Description: Rabbit polyclonal antibody to ANGPTL4
    Specificity: The antibody detects endogenous level of total ANGPTL4 protein.
    Applications: WB, IHC, IF
    Reactivity: Human, Mouse, Rat
    Immunogen: Recombinant protein of human ANGPTL4.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: Antibodies were purified by affinity purification using immunogen.
    Concentration: 1.0mg / ml
    Formulation: Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    Storage: Store at -20?C
    Function: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation (By similarity).
    Tissue Specificity: Expressed at high levels in the placenta, heart, liver, muscle, pancreas and lung but expressed poorly in the brain and kidney.
    Post-Translational Modification: N-glycosylated.
    Cellular locations: Secreted. Secreted > Extracellular space > Extracellular matrix.

    The unprocessed form interacts with the extracellular matrix. This may constitute a dynamic reservoir, a regulatory mechanism of the bioavailability of ANGPTL4 (By similarity).
    Database Links:
  • Entrez Gene: 51129?Human
  • Entrez Gene: 57875?Mouse
  • Entrez Gene: 362850?Rat
  • Omim: 605910?Human
  • SwissProt: Q9BY76?Human
  • SwissProt: Q9Z1P8?Mouse
  • SwissProt: Q6TMA8?Rat
  • Unigene: 9613?Human
  • Unigene: 196189?Mouse
  • Unigene: 119611?Rat
  • Synonyms:
  • Angiopoietin like 4 Antibody
  • Angiopoietin related protein 4 Antibody
  • Angiopoietin-like 4 Antibody
  • Angiopoietin-like protein 4 Antibody
  • Angiopoietin-related protein 4 Antibody
  • ANGL4_HUMAN Antibody
  • ANGPT L2 Antibody
  • ANGPT L4 Antibody
  • ANGPTL2 Antibody
  • Angptl4 Antibody
  • ARP4 Antibody
  • Fasting induced adipose factor Antibody
  • FIAF Antibody
  • HARP Antibody
  • Hepatic angiopoietin related protein Antibody
  • Hepatic fibrinogen/angiopoietin related protein Antibody
  • Hepatic fibrinogen/angiopoietin-related protein Antibody
  • HFARP Antibody
  • NL2 Antibody
  • Peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin related protein Antibody
  • PGAR Antibody
  • pp1158 Antibody
  • PPARG angiopoietin related protein Antibody
  • PSEC0166 Antibody
  • TGQTL Antibody
  • UNQ171 Antibody
  • Weakly similar to angiopoietin 1 [H.sapiens] Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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