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Anti-Synaptophysin Antibody

品牌：Antibodies

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规格：2ml

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Anti-Synaptophysin Antibody

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Name:	Anti-Synaptophysin Antibody See all Synaptophysin primary antibodies
Description:	Rabbit monoclonal (SP11) antibody to Synaptophysin.
Specificity:	Synaptophysin, 38 kDa protein in neurectodermal tissue.
Applications:	IHC
Reactivity:	Human, Bovine, Mouse, Rat
Immunogen:	Synthetic peptide corresponding to the C-terminus of human Synaptophysin.
Host:	Rabbit
Clonality:	Monoclonal
Clone:	SP11
Isotype:	IgG
Conjugate:	Unconjugated
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.3, with 0.09% Sodium Azide.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
Tissue Specificity:	Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
Sequence Similarities:	Belongs to the synaptophysin/synaptobrevin family.
Post-Translational Modification:	Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
Cellular locations:	Cytoplasmic vesicle > Secretory vesicle > Synaptic vesicle membrane. Cell junction > Synapse > Synaptosome.
Database Links:	Entrez Gene: 280937?Cow Entrez Gene: 6855?Human Entrez Gene: 20977?Mouse Entrez Gene: 24804?Rat Omim: 313475?Human SwissProt: P20488?Cow SwissProt: P08247?Human SwissProt: Q62277?Mouse SwissProt: P07825?Rat Unigene: 632804?Human Unigene: 223674?Mouse Unigene: 11067?Rat
Synonyms:	Major synaptic vesicle protein p38 Antibody MRX96 Antibody MRXSYP Antibody Syn p38 Antibody Synaptophysin Antibody Syp Antibody SYPH Antibody SYPH_HUMAN Antibody SypI Antibody
Information:	Target information shown above is from the UniProt Consortium.