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Anti-HIST3H3 Antibody |产品详情|进口橙子视频旧款采购网




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    上海橙子视频app安卓下载生物科技公司
    Tel:400-968-7988    021-33779008
    Anti-HIST3H3 Antibody
    品牌:Antibodies
    货号:
    规格:50µl
    货期:

    Anti-HIST3H3 Antibody

    商品详情 参考文献 相关资料
    Name: Anti-HIST3H3 Antibody
    See all HIST3H3 primary antibodies
    Description: Rabbit polyclonal antibody to HIST3H3.
    Applications: WB, IHC, IF, IP, ChIP
    Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200, IP: 1:50 - 1:200, ChIP: 1:50 - 1:200.
    Reactivity: Human, Mouse, Rat
    Immunogen: A synthetic peptide of human HIST3H3.
    Host: Rabbit
    Clonality: Polyclonal
    Isotype: IgG
    Conjugate: Unconjugated
    Purification: Affinity purification.
    Product Form: Liquid
    Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
    Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
    Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    Tissue Specificity: Expressed in testicular cells.
    Sequence Similarities: Belongs to the histone H3 family.
    Post-Translational Modification: Acetylation is generally linked to gene activation. Acetylation on Lys-10 (H3K9ac) impairs methylation at Arg-9 (H3R8me2s). Acetylation on Lys-19 (H3K18ac) and Lys-24 (H3K24ac) favors methylation at Arg-18 (H3R17me). Acetylation at Lys-123 (H3K122ac) by EP300/p300 plays a central role in chromatin structure: localizes at the surface of the histone octamer and stimulates transcription, possibly by promoting nucleosome instability (By similarity).
    Cellular locations: Nucleus. Chromosome.
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