Anti-Antithrombin III (human, native) ABS 014-22 ABS 014-22|产品详情|进口橙子视频旧款采购网

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Anti-Antithrombin III (human, native) ABS 014-22

品牌：

货号：ABS 014-22

规格：200 µg

货期：

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Anti-Antithrombin III (human, native)

商品详情参考文献相关资料

Cat. No.: HYB 230-01B
Product name: Anti-Antithrombin III (human, native)
Description: Mouse monoclonal antibody, Biotinylated
Specificity: HYB 230-01 is specific for human Antithrombin III (AT III) native form
Immunogen: Antithrombin III isolated from human plasma
Application: ELISA
Species reactivity (positive): Human
Species reactivity (negative): Not determined
Subclass: IgG1/k
Clone number: 1 B7
Epitope: Epitope specificity differs from that of HYB 230-04, HYB 228-10 and HYB 228-12.
Content: Available in 100 µL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification: Biotinylated
Form: Liquid
Solvent: 0.01 M phosphate buffer, pH 7.4, containing 0.14 M NaCl and 15 mM sodium azide
Storage: 4-8ºC without exposure to light. No precautions necessary during handling.
Target: Antithrombin III (AT III) is a single chain glycoprotein of molecular mass 58 kDa with four glycosylation sites and three intra-molecular disulfide bonds. AT III is normally present in human plasma at a concentration of approx. 12.5 mg/dl. It is the major inhibitor of thrombin. Inactivation of thrombin by AT-III occurs by formation of a covalent bond resulting in an inactive 1:1 stoichiometric complex between the two components.

Application 1: ELISA
HYB 230-01 reacts strongly with native AT III. Strong reaction is seen in ELISA with native AT III coated directly onto the microtiter well. In a sandwich ELISA setup, HYB 230-01B acts as a detection antibody in conbination with ABS 014-22 as capture antibody to measure Thrombin-Antithrombin (TAT) complexes.

The calibration curve of a sandwich assay for TAT (Thrombin-antithrombin) using ABS 014-22 as capture antibody and HYB 230-01B as the biotinylated detection antibody.