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Anti-NGAL (rat) ABS 039-15 ABS 039-15|产品详情|进口橙子视频旧款采购网




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    Anti-NGAL (rat) ABS 039-15
    品牌：
    货号：ABS 039-15
    规格：200 µg
    货期：

    Anti-NGAL (rat)
    商品详情 参考文献 相关资料
    Cat. No.
    ABS 039-15
    Product name
    Anti-NGAL (rat)
    Description

    Mouse monoclonal antibody

    Specificity

    ABS 039-15 binds rat NGAL (neutrophil gelatinase-associated lipocalin)

    Immunogen

    Recombinant rat NGAL precursor with C-terminal His-tag coupled to carrier

    Application
    ELISA
    Species reactivity (positive)
    Rat
    Species reactivity (negative)
    Human, pig, dog, mouse
    Subclass

    IgG1/k

    Gene ID
    170496
    Clone number
    15
    Epitope

    Not determined

    Content

    Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

    Purification
    Protein-A purified
    Form
    Liquid
    Solvent
    0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
    Storage
    4-8ºC without exposure to light. No precautions necessary during handling.
    Target

    Rat NGAL, so called because it is the ortholog of human neutrophil gelatinase-associated lipocalin (NGAL), is also called lipocalin 2, 25-kDa alpha 2-microglobulin-related protein or neu-related lipocalin. It is expressed by neutrophils and various epithelial cells, including tubular cells of the kidney. It is involved in physiological processes such as the binding of siderophore iron and tissue growth and regeneration. It is up-regulated in a variety of pathological situations including infection, inflammation, renal injury and certain adenocarcinomas.

    Application 1

    ELISA

    ABS 039-15 binds free rat NGAL in solution. ABS 039-15 (as capture antibody) forms a sandwich ELISA pair with ABS 039-32 (as biotinylated detection antibody) for measuring rat NGAL (measuring range 4-400 pg/mL in an optimized assay).
     
    The figure illustrates the calibration curve of a sandwich assay with ABS 039-15 as the capture antibody and ABS 039-32B as the biotinylated detection antibody.

    1. Bangert et al (2013) The Monomer is the Major Form of NGAL in Urine and Plasma in Severe Sepsis J Am Soc Nephrol 24: 368A

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