Description
The ViPrimePLUS Human T-lymphotropic Virus 1 RT-qPCR Kit is a Taqman probe-based real-time PCR assay for the detection of Human T-lymphotropic Virus 1 genome in clinical samples (e.g. blood).
Human T-Lymphotropic virus (HTLV) is a RNA retrovirus that predominantly affects the T lymphocytes in human. The Human Immunodeficiency virus (HIV) was once categorized in the HTLV genus before the reclassification in 1983. After 30 years from the initial discovery, 4 types of HTLV have been identified and among them, the most significant two are the HTLV 1 and 2, which have affected about 15-20million people worldwide. HTLV-1 is divided into 6 subclasses which are endemic to different regions. It causes multiple disorders such as the often fatal leukaemia, debilitative myelopathy, uveitis and dermatitis. However, HTLV-2, which consists of 4 subtypes, is associated with milder neurological disorder and chronic pulmonary infections. The novel HTLV-3 and HTLV-4 have been isolated in a few cases but they have little clinical significance. Mode of transmission is via breast milk, sexual contact and intravenous drug abuse.
ViPrimePLUS Human T-lymphotropic Virus 1 RT-qPCR Kit is intended for research use only.
Kit Component
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HTLV1 Primers and Probe Mix (HTLV1 PPM)
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Positive Control
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Internal Extraction Control Primers and Probe Mix (IEC PPM)
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Internal Extraction Control (IEC DNA)
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Nuclease Free Water
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Template Preparation Buffer
Product Specification
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Technology
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Taqman probe-based real-time PCR assay
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Type of Nucleic Acid Kit
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RNA
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Kit Storage
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Shipped in room temperature, store at -20℃ on arrival
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Sample Material
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Clinical samples (e.g. blood)
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Gene Target
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Polymerase gene (Pol)
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Detection Limit
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10 to <100 copies per reaction
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Sensitivity & Specificity
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Ct value 28±3 with probability of 95%
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Controls Included
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• Internal Extraction Control (IEC) as inhibition control
• Positive control
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Channels
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• FAM channels detect pathogen amplicons
• VIC/HEX channel detects IEC amplicons
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Ordering Information
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Catalog No
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Description
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Pack Size
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QM5057
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ViPrimePLUS Human T-lymphotropic Virus 1 RT-qPCR Kit
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150 reactions
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Download
Manual
VViPrimePLUS Human T-lymphotropic Virus 1 RT-qPCR Kit
