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    上海橙子视频app安卓下载生物科技公司
    Tel:400-968-7988    021-33779008
    Monoclonal Antibody to Human C5
    品牌:Quidel
    货号: A217
    规格:100 µL
    货期:现货

    商品详情 参考文献 相关资料

    产品介绍

    品名

    Monoclonal Antibody to Human C5

    货号

    A217   

    规格

    100 µL

     同种型

     IgG1k

    蛋白质浓度

     > 1.0 mg/mL

    纯度

    ≥ 95% by SDS PAGE 

    缓冲液

    Borate Buffered Saline (pH 8.4 ± 0.2)

    物种交叉反应

     Human, baboon

    储存

    torage: ≤ 30 Days 2-8˚C 

    > 30 Days ≤ –20˚C

    使用说明

    For Research Use Only. Not for use in diagnostic procedures

    产品描述

    A murine monoclonal antibody to an epitope on C5.

    This monoclonal antibody was raised against purified human C. It is specific for an antigen expressed on the C5 but not on MAC Complex. This antibody inhibits the lysis of EA and will not bind to MAC bound to a membrane.

    Quidel's C5 monoclonal antibody has been used in a variety of experimental techniques including EIA, Western Blot, and RIA

    特异性

    The specificity of the monoclonal antibody was established by ELISA and radioimmunoassay (RIA). Using RIA, this monoclonal antibody was shown to bind radiolabeled C5 protein. Specificity was confirmed by functional inhibition of C5. In this study, ~17 ng of the Anti-Human C5 monoclonal antibody gave 50% inhibition of the lysis of antibody-coated sheep erythrocytes (EA) in an assay designed to measure C5 hemolytic function. The assay used highly purified C5 protein, EA and normal human serum which was immunochemically depleted of C5. The antibody does not recognize TCC deposited on membranes. 

    应用

    参考资料

     1、Sandoval, A., Rong A., et al. Distal recognition site for classical pathway convertase located in the C345C/Netrin module of complement component C5, J. Immunol 165:2 1066-1073., 2000.

    2、Barbashov, S. Wang, C., Nicholson-Weller, A. Serum amyloid P component forms a stable complex with human C5b-6, J. Immunol. 158:3830-3835, 1997.

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