Cyanine5 NHS ester 13020|产品详情|进口橙子视频旧款采购网

订购货号	产品名称及规格	价格（￥）
13020	Cyanine5 NHS ester, 1 mg	1430.00
23020	Cyanine5 NHS ester, 5 mg	2730.00
43020	Cyanine5 NHS ester, 25 mg	5330.00
53020	Cyanine5 NHS ester, 50 mg	9035.00
63020	Cyanine5 NHS ester, 100 mg	15470.00

在过去的几年里，CY5荧光团已经成为生命科学研究和诊断领域非常流行的分子标记物。这些荧光素的*强发射光为红光，在这个范围大多数CCD检测器具有*大检测灵敏度，而且是生物物质低背景区。染料的颜色是非常强烈的，因此在凝胶电泳中低至1nmol的量都能被肉眼观测到。CY5 NHS ester是用于标记多肽、蛋白和寡核苷酸的氨基基团的活性染料。在标记反应中该染料需要少量的有机共溶剂（如DMF，DMSO）（请参照橙子视频app安卓下载的推荐手册以获得更多帮助信息）。对于可溶性蛋白、各种各样的多肽和寡核苷酸而言，这种染料是非常理想而且成本低廉的。该染料在有机溶剂对小分子物质的标记也是非常有效的。对于更多的精细目标物，如易降解蛋白，如果DMF或DMSO会对其有影响，可以考虑water-soluble Cy5 NHS ester（水溶性Cy5 NHS ester染料），因为它们不需要有机溶剂助溶，而且具有和荧光染料类似的性质。

CY5荧光团可以与很多的仪器如荧光显微镜、成像仪、扫描仪、荧光分析仪等相兼容。许多的CY5衍生物——CY5 NHS ester可以替代Alexa Fluor 647和 DyLight 649等活化酯（activated esters）。

推荐手册

氨基分子的NHS酯标记

Cy® is a trademark of GE Healthcare.

General properties

Appearance:	dark blue powder
Molecular weight:	616.19
Molecular formula:	C₃₆H₄₂ClN₃O₄
CAS number:	1032678-42-4, 350686-88-3
Solubility:	good in polar (DMSO, DMF) and chlorinated (DCM, chlroform) organic solvents, low solubility in water
Quality control:	NMR 1H (95%) and 13C, TLC, functional testing
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	Download

Spectral properties

Excitation maximum, nm:	646
Extinction coefficient at excitation maximum, Lmol-1cm-1:	250000
Emission maximum, nm:	662
Fluorescence quantum yield:	0.2

Product citations

Geertsema, H.J.; Kulczyk, A.W.; Richardson, C.C.; van Oijen, A.M. Single-molecule studies of polymerase dynamics and stoichiometry at the bacteriophage T7 replication machinery.Proceedings of the National Academy of Sciences, 2014, 111(11), 4073-4078. doi:10.1073/pnas.1402010111
Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p
Hu, X.; Wang, Q.; Liu, Y.; Liu, H.; Qin, C.; Cheng, K.; Robinson, W.; Gray, B.D.; Pak, K.Y.; Yu, A. et al.Optical imaging of articular cartilage degeneration using near-infrared dipicolylamine probes.Biomaterials, 2014, 35(26), 7511-7521. doi: 10.1016/j.biomaterials.2014.05.042
Novo, L.; Rizzo, L.Y.; Golombek, S.K.; Dakwar, G.R.; Lou, B.; Remaut, K.; Mastrobattista, E.; van Nostrum, C.F.; Jahnen-Dechent, W.; Kiessling, F. et al. Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy. Journal of Controlled Release, 2014, 195, 162-175. doi: 10.1016/j.jconrel.2014.08.028
Zhang, Y.; Ge, C.; Zhu, C.; Salaita, K. DNA-based digital tension probes reveal integrin forces during early cell adhesion. Nature Communications, 2014, 5, 5167-5167. doi: 10.1038/ncomms6167
Chen, H.; Xiao, L.; Anraku, Y.; Mi, P.; Liu, X.; Cabral, H.; Inoue, A.; Nomoto, T.; Kishimura, A.; Nishiyama, N. et al. Polyion Complex Vesicles for Photoinduced Intracellular Delivery of Amphiphilic Photosensitizer. Journal of the American Chemical Society, 2014, 136(1), 157-163. doi:10.1021/ja406992w
Albertazzi, L.; Martinez-Veracoechea, F.J.; Leenders, C.M.A.; Voets, I.K.; Frenkel, D.; Meijer, E.W.Spatiotemporal control and superselectivity in supramolecular polymers using multivalency.Proceedings of the National Academy of Sciences, 2013, 110(30), 12203-12208. doi:10.1073/pnas.1303109110
Cheng, M.-C.; Leske, A.T.; Matsuoka, T.; Kim, B.C.; Lee, J.; Burns, M.A.; Takayama, S.; Biteen, J.S. Super-Resolution Imaging of PDMS Nanochannels by Single-Molecule Micelle-Assisted Blink Microscopy.The Journal of Physical Chemistry B, 2013, 117(16), 4406-4411. doi: 10.1021/jp307635v
Haller, A.; Altman, R.B.; Souliere, M.F.; Blanchard, S.C.; Micura, R. Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution. Proceedings of the National Academy of Sciences, 2013, 110(11), 4188-4193. doi: 10.1073/pnas.1218062110
He, H.; Chen, S.; Zhou, J.; Dou, Y.; Song, L.; Che, L.; Zhou, X.; Chen, X.; Jia, Y.; Zhang, J. et al.Cyclodextrin-derived pH-responsive nanoparticles for delivery of paclitaxel. Biomaterials, 2013, 34(21), 5344-5358. doi: 10.1016/j.biomaterials.2013.03.068
Rimpelová, S.; B?íza, T.; Králová, J.; Záruba, K.; Kejík, Z.; Císa?ová, I.; Martásek, P.; Ruml, T.; Král, V.Rational Design of Chemical Ligands for Selective Mitochondrial Targeting. Bioconjugate Chemistry,2013, 24(9), 1445-1454. doi: 10.1021/bc400291f
Soulière, M.F.; Altman, R.B.; Schwarz, V.; Haller, A.; Blanchard, S.C.; Micura, R. Tuning a riboswitch response through structural extension of a pseudoknot. Proceedings of the National Academy of Sciences, 2013, 110(35), E3256-E3264. doi: 10.1073/pnas.1304585110
Yang, H.; Mao, H.; Wan, Z.; Zhu, A.; Guo, M.; Li, Y.; Li, X.; Wan, J.; Yang, X.; Shuai, X. et al. Micelles assembled with carbocyanine dyes for theranostic near-infrared fluorescent cancer imaging and photothermal therapy. Biomaterials, 2013, 34(36), 9124-9133. doi: 10.1016/j.biomaterials.2013.08.022
Pecqueur, L.; Duellberg, C.; Dreier, B.; Jiang, Q.; Wang, C.; Pluckthun, A.; Surrey, T.; Gigant, B.; Knossow, M. A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end. Proceedings of the National Academy of Sciences, 2012, 109(30), 12011-12016. doi:10.1073/pnas.1204129109
Sparks, J.; Slobodkin, G.; Matar, M.; Congo, R.; Ulkoski, D.; Rea-Ramsey, A.; Pence, C.; Rice, J.; McClure, D.; Polach, K.J. et al. Versatile cationic lipids for siRNA delivery. Journal of Controlled Release, 2012, 158(2), 269-276. doi: 10.1016/j.jconrel.2011.11.006

Chiang, W.-L.; Lin, T.-T.; Sureshbabu, R.; Chia, W.-T.; Hsiao, H.-C.; Liu, H.-Y.; Yang, C.-M.; Sung, H.-W. A rapid drug release system with a NIR light-activated molecular switch for dual-modality photothermal/antibiotic treatments of subcutaneous abscesses. Journal of Controlled Release,2015, 199, 53–62. doi: 10.1016/j.jconrel.2014.12.011
B?íza, T.; Rimpelová, S.; Králová, J.; Záruba, K.; Kejík, Z.; Ruml, T.; Martásek, P.; Král, V. Pentamethinium fluorescent probes: The impact of molecular structure on photophysical properties and subcellular localization. Dyes and Pigments, 2014, 107, 51-59. doi: 10.1016/j.dyepig.2013.12.021
Bamrungsap, S.; Apiwat, C.; Chantima, W.; Dharakul, T.; Wiriyachai****, N. Rapid and sensitive lateral flow immunoassay for influenza antigen using fluorescently-doped silica nanoparticles.Microchimica Acta, 2014, 181(1–2), 223-230. doi: 10.1007/s00604-013-1106-4
Duellberg, C.; Trokter, M.; Jha, R.; Sen, I.; Steinmetz, M.O.; Surrey, T. Reconstitution of a hierarchical +TIP interaction network controlling microtubule end tracking of dynein. Nature Cell Biology, 2014, 16(8), 804-811. doi: 10.1038/ncb2999

橙子视频app安卓下载,91橙子视频,橙子视频旧款,橙子视频在线官网

订购货号产品名称及规格价格（￥） 13020 Cyanine5 NHS ester, 1 mg 1430.00 23020 Cyanine5 NHS ester, 5 mg 2730.00 43020 Cyanine5 NHS ester, 25 mg 5330.00 53020 Cyanine5 NHS ester, 50 mg 9035.00 63020 Cyanine5 NHS ester, 100 mg 15470.00

Cyanine5 NHS ester

详细描述

Product citations

橙子视频app安卓下载,91橙子视频,橙子视频旧款,橙子视频在线官网

订购货号 产品名称及规格 价格（￥） 13020 Cyanine5 NHS ester, 1 mg 1430.00 23020 Cyanine5 NHS ester, 5 mg 2730.00 43020 Cyanine5 NHS ester, 25 mg 5330.00 53020 Cyanine5 NHS ester, 50 mg 9035.00 63020 Cyanine5 NHS ester, 100 mg 15470.00

Cyanine5 NHS ester

详细描述

Product citations

订购货号产品名称及规格价格（￥） 13020 Cyanine5 NHS ester, 1 mg 1430.00 23020 Cyanine5 NHS ester, 5 mg 2730.00 43020 Cyanine5 NHS ester, 25 mg 5330.00 53020 Cyanine5 NHS ester, 50 mg 9035.00 63020 Cyanine5 NHS ester, 100 mg 15470.00